create new tag
, view all tags


T-box, brain, 1b


Rate Information on this Page
Score: 0, My vote: 0, Total votes: 0
GeneName tbr1b
Aliases tbr1, zf-tbr1
Description T-box, brain, 1b
GenomicLocation Chromosome 9: 52,776,692-52,782,926 reverse strand
ExternalIDs Ensembl:ENSDARG00000004712, Unigene ID Dr.10723,ZFIN:ZDB-GENE-000323-1
TranscriptID ENSDART00000006612; ENSDART00000125742
mRNA NM_001115090.2
GeneDescription This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes.
GeneFunction It modulates the frequency, rate or extent of cellular DNA-dependent transcription.
GeneCloning tbr1b Contained in: [Fosmid] CH1073-192A6
GeneStructure The gene codes for 2 transcripts.It cocnsits of 6 exons and the transcript (ENSDART00000006612) has a length of 3855 bps and codes for a protein (ENSDARP00000019930) of 676 aa residues. The other transcript (ENSDART00000125742) consists of 7 exons with a transcript length of 2203 and codes for a protein of 437 aa residue.
Protein ENSDARP00000019930; ENSDARP00000105823
ProteinDomainandFamilies has domain [InterPro:IPR001699]; [InterPro:IPR008967]; [InterPro:IPR018186]
Motifs has motif [PROSITE:PS50252] ; [PROSITE:PS01283]; [PROSITE:PS01264]; [Pfam:PF00907 ]
Expression Arrar |Express ENSDARG00000004712
GeneOntology GO:0006355
Orthologs Entrez: [Gene:10716]
VariationAndRepeats RSID:rs180033685; RSID:rs41008120; RSID:rs41008120; RSID:rs180033694

RelatedPubMedArticles Mione, M., Shanmugalingam, S., Kimelman, D., and Griffin, K. (2001) Overlapping expression of zebrafish T-brain-1 and eomesodermin during forebrain development. Mech. Dev. 100(1):93-97 PubMed: 11118891NCBI Resource Coordinators.: Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 41(Database issue):D8-D20. 2013. PMID:23193264
Kersey, P. J.; Allen, J. E.; Christensen, M.; et al.: Ensembl Genomes 2013: scaling up access to genome-wide data. Nucleic Acids Res. 2013. PMID:24163254
Sigrist, C. J. A.; de, Castro, E; Cerutti, L; Cuche, B. A.; Hulo, N.; Bridge, A.; Bougueleret, L. Xenarios, I.: New and continuing developments at PROSITE. Nucleic Acids Res. doi: 10.1093/nar/gks1067. 2012. PMID:23161676
Punta, M.; Coggill, P. C.; Eberhardt, et al.: The Pfam protein families database. Nucleic Acids Res. 40(Database Issue):D290-D301. 2012. PMID:22127870
Hunter, S.; Jones P.; Mitchell A.; et al.: Interpro in 2011: new developments in the family and domain prediction database. Nucleic Acids Res. doi: 10.1093/nar/gkr948. 2011. PMID:22096229
Carbon, S.; Ireland, A.; Mungall, C. J.; Shu, S.; Marshall, B.; Lewis, S.; AMIGO Hub; Web Presence Working Group.: AMIGO: online access to ontology and annotation data. Bioinformatics. 25(2):288-9. 2009. PMID:19033274
Ashburner, M.; Ball, C. A.; Blake, J. A.; et al. The Gene Ontology Consortium.: Gene ontology: tool for the unification of biology. Nat. Genet. 25(1):25-9. 2000. PMID:10802651
Sherry, S. T.; Ward, M. H.; Kholodov, M.; Baker, J.; Phan, L.; Smigielski, E. M.; Sirotkin, K.: dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 1;29(1):308-11. 2001. PMID:11125122
Bradford, Y.; Conlin, T.; Dunn, N.; et al.: ZFIN: enhancements and updates to the zebrafish model organism database. Nucleic Acids Res. 39(suppl 1):D822-D829. 2011. PMID:21036866
Kapushesky, M.; Adamusiak, T.; Burdett, T.; et al.: Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments. Nucleic Acids Res. 40(Database isue):D1077-81. 2012. PMID:22064864

Web resources:
NCBI: http://www.ncbi.nlm.nih.gov/
PFAM: http://pfam.sanger.ac.uk/
PROSITE: http://prosite.expasy.org/
Interpro: http://www.ebi.ac.uk/interpro/
ZFIN: http://zfin.org/
Expression Atlas (EMBL): http://www.ebi.ac.uk/gxa/
Ensembl: http://asia.ensembl.org/Danio_rerio/
Database of Single Nucleotide Polymorphisms (dbSNP). Bethesda (MD): National Center for Biotechnology Information, National Library of Medicine.: http://www.ncbi.nlm.nih.gov/SNP/
PRINTS from Genomenet: http://www.genome.jp/
European Nucleotide Archive: http://www.ebi.ac.uk/ena/home
UNIGENE: http://www.ncbi.nlm.nih.gov/unigene/
AMIGO Gene Ontology: http://amigo.geneontology.org
Topic revision: r2 - 2013-07-06 - ShrutiKapoor
This site is powered by the TWiki collaboration platform Powered by PerlCopyright © 2008-2017 by the contributing authors. All material on this collaboration platform is the property of the contributing authors.
Ideas, requests, problems regarding TWiki? Send feedback

mersin escort bayan adana escort bayan izmit escort ankara escort bursa escort